Medicines which have amount restrictions affiliated with Each and every prescription. This restriction ordinarily limitations the quantity in the drug that should be lined.
Advarsler og forsiktighetsregler Snakk med lege eller apotek før du bruker Modiodal dersom du Har hjerteproblemer eller høyt blodtrykk. Legen din må sjekke dette regelmessig mens du tar Modiodal.
EMA ble opprettet i 1995 for å sikre greatest mulig utnyttelse av Europas vitenskapelige ressurser for evaluering av, tilsyn med og overvåkning av legemidler.
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Modafinil is each quick-acting and very long-Long lasting. It is actually metabolized while in the liver, and peak plasma concentrations occur inside of two – four several hours, though initial effects could be felt inside an hour.
Keep an eye on Carefully (1)levoketoconazole will improve the amount or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
Kvalme er en ubehagsfornemmelse i mellomgulv og mage, som ofte er fulgt av en fileølelse av at en vil more info kaste opp.
Stiripentol is really a CYP3A4 inhibitor and inducer. Keep an eye on CYP3A4 substrates coadministered with stiripentol for amplified or lessened effects. CYP3A4 substrates might need dosage adjustment.
nelfinavir will increase the stage or outcome of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Chemelli et al (1999) examined fos-reactivity in orexin neurons of mice specified modafinil just before sacrifice and found a substantially larger activation of orexin neurons with modafinil than with placebo.
modafinil will lessen the level or influence of mavacamten by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
cannabidiol will improve the level or influence of modafinil by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Observe Closely. Contemplate minimizing the dose of delicate CYP2C19 substrates, as clinically correct, when coadministered with cannabidiol.
Outcome of coadministration of the twin CYP3A4 and CYP2C19 inhibitor with fedratinib has not been examined.
Angitt pris er maksimal utsalgspris fra apotek. Pakninger som selges uten resept er angitt med stjerne *. Det er fri prisfastsettelse for pakninger som selges uten resept, og maksimal utsalgspris kan derfor ikke angis.